Ciprofloxacin Sandoz 500mg Tablets 14
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General Information
Ciprofloxacin Sandoz®
ciprofloxacin hydrochloride tablets

Consumer Medicine Information

This leaflet answers some common questions about Ciprofloxacin Sandoz.

It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking this medicine against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine. You may need to read it again.

This medicine is used to treat infections of the lungs, skin, bones and joints, kidney and bladder, prostate and bowel.

It contains the active ingredient ciprofloxacin hydrochloride.

Ciprofloxacin hydrochloride belongs to a group of medicines called quinolone antibiotics.

It works by killing the bacteria that are causing your infection.

Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed it for another reason.

This medicine is not addictive.

This medicine is available only with a doctor’s prescription.

When you must not take it
Do not take this medicine if you have an allergy to:

ciprofloxacin hydrochloride, the active ingredient, or to any of the other ingredients listed at the end of this leaflet under Product Description.
any other similar medicines such as quinolone antibiotics including nalidixic acid.
Some of the symptoms of an allergic reaction may include:

shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin.
Do not take this medicine if you are also taking a medicine called tizanidine (Zanaflex®), used as a muscle relaxant.

Do not breastfeed if you are taking this medicine. The active ingredient in Ciprofloxacin Sandoz passes into breast milk and there is a possibility that your baby may be affected.

Do not give this medicine to children and growing adolescents unless you are told by your doctor to do so. Safety and effectiveness in children and growing adolescents have not been established.

Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.

If you are not sure whether you should start taking this medicine, talk to your doctor.

Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.

Tell your doctor if you have or have had any of the following medical conditions:

any type of allergic reaction to ciprofloxacin or quinolone antibiotics
you suffer from fits (seizures, convulsions)
have had a stroke
kidney disease
myasthenia gravis (a condition where your muscles become weak and tire easily)
a history of tendon problems associated with quinolone antibiotics
any other medical problems.
Tell your doctor if you have previously taken corticosteroids. You may be at increased risk of swelling of the tendons. Symptoms include pain, tenderness and sometimes restricted movement.

Tell your doctor if you are pregnant or plan to become pregnant or are breastfeeding. Your doctor can discuss with you the risks and benefits involved.

If you have not told your doctor about any of the above, tell him/her before you start taking Ciprofloxacin Sandoz.

Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.

Some medicines and Ciprofloxacin Sandoz may interfere with each other. These include:

theophylline, a medicine used to treat asthma
anticoagulants, medicines used to stop blood clots such as warfarin
probenecid, a medicine used to treat gout
glibenclamide, a medicine used to treat diabetes
cyclosporin, a medicine used in organ transplantation
methotrexate, a medicine used in cancer and to treat arthritis
NSAIDs (non-steroidal anti-inflammatory drugs), medicines used to treat pain, swelling and arthritis
ropinirole, a medicine used to treat Parkinson’s disease and restless legs syndrome
lidocaine, an anaesthetic
multivitamins, mineral supplements and other medicines containing iron, zinc, magnesium, aluminium or calcium
sucralfate, a medicine used to treat duodenal or stomach ulcers
omeprazole, a medicine used to treat ulcers and other conditions where the stomach produces too much acid
metoclopramide, a medicine used to relieve nausea, vomiting and stomach pain
some antiviral medicines used to treat HIV infection, such as didanosine
sevelamer, a medicine used to treat high blood levels of phosphorus in patients with kidney disease who are on dialysis
duloxetine, a medicine used to treat depression
clozapine, a medicine used to treat schizophrenia.
These medicines may be affected by Ciprofloxacin Sandoz or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines.

Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.

Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions, ask your doctor or pharmacist for help.

How much to take
The usual adult dosage for most infections is one tablet twice daily for 7 to 14 days.

You may need to take your tablets for a longer period of time for some types of infections.

Your doctor may have prescribed a different dose.

Ask your doctor or pharmacist if you are unsure of the correct dose for you. They will tell you exactly how much to take.

Follow the instructions they give you. If you take the wrong dose, Ciprofloxacin Sandoz may not work as well and your problem may not improve.

How to take it
Swallow the tablets whole with a full glass of water.

When to take Ciprofloxacin Sandoz
Take your medicine at about the same time each day. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.

Take your medicine preferably on an empty stomach, for example, 1 hour before food or 2 hours after food. Food can interfere with the absorption of this medicine. However, they can be taken with or without food.

If you need to take an antacid, multivitamins, mineral supplements and other medicines containing iron, zinc, magnesium, aluminium or calcium, take it at least 2 hours before or 2 hours after your dose of Ciprofloxacin Sandoz. Your doctor and pharmacist will have more information on medicines to avoid while taking this medicine.

How long to take Ciprofloxacin Sandoz
Continue taking your medicine until you finish the pack or for as long as your doctor tells you.

If you forget to take it
Take your dose as soon as you remember, and continue to take it as you would normally.

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.

If you are not sure what to do, ask your doctor or pharmacist.

If you have trouble remembering to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)
Immediately telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much Ciprofloxacin Sandoz. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

Symptoms of an overdose may include drowsiness, nausea, vomiting or little or no urine.

Things you must do
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking Ciprofloxacin Sandoz.

Tell any other doctors, dentists, and pharmacists who treat you that you are taking this medicine.

If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery.

If you develop diarrhoea, tell your doctor or pharmacist immediately. Do this even if it occurs several weeks after you have stopped taking this medicine. Diarrhoea may mean that you have a serious condition affecting your bowel. You may need urgent medical care.

Do not take any medications for diarrhoea without checking with your doctor.

If you become pregnant while taking this medicine, tell your doctor immediately.

Drink plenty of water while you are taking Ciprofloxacin Sandoz. This helps to stop crystals forming in the urine.

If you get a sore white mouth or tongue while taking, or soon after stopping this medicine, tell your doctor or pharmacist. Also tell your doctor if you get vaginal itching or discharge. This may mean that you have a fungal infection called thrush. Sometimes the use of antibiotics allows fungi to grow. Ciprofloxacin Sandoz does not work against fungi.

Things you must not do
Do not take Ciprofloxacin Sandoz to treat any other complaints unless your doctor tells you to.

Do not give your medicine to anyone else, even if they have the same condition as you.

Do not stop taking your medicine or lower the dosage without checking with your doctor. If you do not complete the full course prescribed by your doctor, your infection may not clear completely, or it may return.

Things to be careful of
Avoid excessive exposure to direct sunlight. Your skin may become more prone to sunburn.

Be careful driving or operating machinery until you know how Ciprofloxacin Sandoz affects you. This medicine may cause dizziness and light-headedness in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.

Be careful when drinking alcohol while you are taking this medicine. If you drink alcohol, dizziness and light-headedness may be worse.

Ciprofloxacin Sandoz may increase the stimulatory effects of caffeine.

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Ciprofloxacin Sandoz. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.

Do not be alarmed by the following lists of side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor or pharmacist if you notice any of the following and they worry you:

dizziness or light-headedness
mild stomach upsets such as stomach pains, flatulence or diarrhoea
loss of appetite or altered taste
heartburn (dyspepsia)
feeling sick (nausea) or vomiting
discharge and itching in the vagina
irritability, agitation or confusion
difficulty sleeping.
These are the more common side effects of the medicine, and are usually mild and short-lived

Tell your doctor immediately if you notice any of the following:

pain, inflammation or rupture of the Achilles tendon (which extends from the calf to the heel of the foot) or other tendons
increased sensitivity of the skin to sunlight, resulting in getting sunburnt more easily than usual
joint/muscle pain or cramping
symptoms of low blood sugar (hypoglycaemia), which may include sweating, weakness, dizziness, trembling and a fast pounding heartbeat.
The above list includes serious side effects that may require medical attention. If you experience any of the above side effects, Ciprofloxacin Sandoz may need to be stopped. Serious side effects are rare

If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:

swelling of the face, lips, mouth or throat
wheezing or difficulty breathing
severe skin rashes, hives, itching or blistering or peeling of the skin
severe abdominal or stomach cramps
severe, watery or bloody diarrhoea, even if it occurs several weeks after stopping this medicine
fits (seizures or convulsions)
hallucinations, self-endangering behaviour
yellowing of the skin and/or eyes, also called jaundice
heart beating faster than normal
visual disturbances
ringing in the ear, loss of hearing
passing little or no urine
dark coloured urine.
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are rare.

Rarely, there can be a worsening of the symptoms of myasthenia gravis. This is a condition in which the muscles become weak and tire easily, causing drooping eyelids, double vision, difficulty speaking and swallowing, and/or muscle weakness in the arms or legs.

Tell your doctor or pharmacist if you notice anything else that is making you feel unwell. Other side effects not listed above may also occur in some people.

Some of these side effects (for example kidney, liver or blood problems) can only be found when your doctor does tests from time to time to check your progress.

After taking Ciprofloxacin Sandoz
Tell your doctor immediately if you notice any of the following side effects, particularly if they occur several weeks after stopping treatment with Ciprofloxacin Sandoz:

severe abdominal or stomach cramps
watery and severe diarrhoea, which may also be bloody
fever, in combination with one or both of the above.
These are rare but serious side effects. You may have a serious condition affecting your bowel. Therefore, you may need urgent medical attention.

Do not take any diarrhoea medicine without first checking with your doctor.

Keep your medicine in the original container.

If you take it out of its original container it may not keep well.

Keep your medicine in a cool dry place where the temperature stays below 25°C.

Do not store Ciprofloxacin Sandoz or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any medicine that is left over.

What it looks like
Ciprofloxacin Sandoz comes in three types of tablets:

Ciprofloxacin Sandoz 250mg - white, round, film-coated tablets with a breaking notch on one side, embossed with ‘cip 250’.
Ciprofloxacin Sandoz 500mg - white, oblong, film-coated tablets with a breaking notch on both sides, embossed with ‘cip 500’.
Ciprofloxacin Sandoz 750mg - white, oblong, film-coated tablets with a breaking notch on both sides, embossed with ‘cip 750’.
Available in blisters of 14 tablets.

Active ingredients:

Ciprofloxacin Sandoz 250mg - 250mg ciprofloxacin (as ciprofloxacin hydrochloride)
Ciprofloxacin Sandoz 500mg - 500mg ciprofloxacin (as ciprofloxacin hydrochloride)
Ciprofloxacin Sandoz 750mg - 750mg ciprofloxacin (as ciprofloxacin hydrochloride).
Inactive ingredients:

colloidal anhydrous silica
magnesium stearate
microcrystalline cellulose
stearic acid
sodium starch glycollate type A
croscarmellose sodium
macrogol 6000
titanium dioxide.
This medicine does not contain lactose, sucrose, gluten, tartrazine or any other azo dyes.

Ciprofloxacin Sandoz is supplied in Australia by:
Sandoz Pty Ltd
ABN 60 075 449 553
Level 4, 100 Harris St
Pyrmont NSW 2009
Tel: 1800 634 500 1800 634 500

This leaflet was revised in January 2010.

Australian Register Numbers
250mg film-coated tablets: AUST R 81460 (blisters)
500mg film-coated tablets: AUST R 81461 (blisters)
750mg film-coated tablets: AUST R 81462 (blisters)

Published by MIMS/myDr May 2010

Consumers should be aware that the information provided by the Consumer Medicines Information (“CMI”) search (“CMI Search”) is for information purposes only and consumers should continue to obtain professional advice from a qualified healthcare professional regarding any condition for which they have searched for CMI. CMI is supplied by the relevant pharmaceutical company for each consumer medical product. All copyright and responsibility for CMI is that of the relevant pharmaceutical company. UBM Medica Australia uses its best endeavours to ensure that at the time of publishing, as indicated on the publishing date for each resource (e.g. “Published by MIMS/myDr January 2007”), the CMI provided was complete to the best of UBM Medica Australia’s knowledge. The CMI and the CMI Search are not intended to be used by consumers to diagnose, treat, cure or prevent any disease or for any therapeutic purpose. UBM Medica Australia, its servants and agents shall not be responsible for the continued currency of the CMI, or for any errors, omissions or inaccuracies in the CMI and/or the CMI Search whether arising from negligence or otherwise or from any other consequence arising there from
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